this post was submitted on 07 Jun 2025
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[–] ColeSloth@discuss.tchncs.de 19 points 14 hours ago (2 children)

He's lucky it was just his liver. People who overdose or try to commit suicide with it are not in for a good time or quick death and after it's absorbed into your body it will cause a systemic shutdown of several organs like the kidneys and pancreas. Not just the liver, and there's absolutely no way to counteract this after that first 36 hours. You will die (you aren't getting all of the organs replaced) and it will take days before you succumb. No antidote or life support or anything can be done for you.

You'll feel fine the first day but may have some vomiting. By day 3 the jaundice and stomach pain sets in as the liver is first to show signs of the organs failure and it's no longer possible to counteract the drug. By the fourth day your organs start shutting down and you'll have much more pain and vomiting. All that can be done is get your affairs in order because you'll be dead and in pain while you wait around to die and regret your suicide.

I say suicide because it's almost always intentional. It usually takes 40 325mg pills to cause this, although the liver damage can be caused with 20+ pills in an adult, generally. If you think you've possibly overdosed get to the hospital quick and tell them what you've taken so they can start you on Acytylcystine. If you "feel fine" after the first day or so and think you're all good you may be wrong and when day Tyree rolls around and your feeling bad or jaundiced your liver is already wrecked and can't be fixed.

[–] OmegaLemmy@discuss.online 1 points 11 hours ago (5 children)

What's a better pill to kill yourself with?

[–] joel_feila@lemmy.world 3 points 10 hours ago (1 children)

Just better, a rusty hammer

[–] hakunawazo@lemmy.world 2 points 8 hours ago

Difficult to eat such a mighty meal

[–] Evotech@lemmy.world 4 points 11 hours ago (2 children)
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[–] RBWells@lemmy.world 45 points 18 hours ago (4 children)

Not "even paracetamol". ESPECIALLY paracetamol.

Tylenol/acetaminophen/paracetamol is both weak ass painkiller and really dangerous because the overdose line is low. Here they put it in synthetic opioid drugs, it doesn't help with pain but does make them more dangerous.

[–] Evotech@lemmy.world 5 points 11 hours ago

It’s good at reducing fever

[–] Ledericas@lemm.ee 5 points 15 hours ago* (last edited 15 hours ago) (1 children)

oh yea it isnt as good as other otc nsaids, like ibuprofen and naproxen, or aspirin. oh and that fake pseudoephedrine mimic(phenyleprine) for cogestion, they already said it has no effect whatsoever. its mostly the 1st generation antihistamines doing all the work for your sinuses when you have the cold anyways.

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[–] OmegaLemmy@discuss.online 4 points 11 hours ago

I had intense tummy aches for 15 days where I couldn't walk and needed to keep heat to my belly to even function, once my pain killers didn't work, I didn't push it, I just tried to handle the pain

I cried a lot in that time, it fucking sucked, but it sure was better than liver failure.

[–] Alaik@lemmy.zip 8 points 14 hours ago (4 children)

ITT: People who don't know the difference between acute and chronic ODs and how a smaller amount over a long period can hurt you. 325mg APAP x4 will not kill you short term.

The problem was taking it every day over a long period.

Its still fucking stupid though.

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[–] joel_feila@lemmy.world 9 points 15 hours ago (5 children)
[–] hardcoreufo@lemmy.world 2 points 10 hours ago (1 children)

Asking the real questions.

[–] joel_feila@lemmy.world 1 points 10 hours ago

Kinda surprised you didn't give some it answer

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[–] Flamekebab@piefed.social 36 points 20 hours ago (12 children)

It's bizarre to me that someone can make it to adulthood without knowing that paracetamol specifically is no fucking joke.

[–] raltoid@lemmy.world 23 points 18 hours ago* (last edited 18 hours ago) (1 children)

People look up resources on them and see that the recommended max dose of ibuprofen is lower than paracetamol per day in weight of the active ingredient and stop reading.

They don't get to the part about how the effect per weight isn't the same. Or how damaging paracetamol can be for the liver if you take it regularly or go over the recommend limit. Heavy drinkers especially don't take into account the extra stress on their liver, which is a contributor to the 400-500 deaths it causes every year in the US alone.

Meanwhile ibuprofen makes you feel sick and want to vomit once you start to go over the recommended limit. And if you reach that stage, you basically just stay hydrated to keep your kidneys going and wait for it to pass. Since it usually takes another 2-3 times as much to for the severe effects to occur.


To quote Scrubs:

Dr. Cox: Did you just page me to ask me how much ibuprofen to give Mrs. Lenzner here?

Sunny: Well, I was worried it would exacerbate the patient's

Dr. Cox: It's ibuprofen! Here's what you do. When she wakes up, get her to open her mouth nice and wide, then get some of those ibuprofen pills in your hands and throw them at her. Whatever sticks in there, that's the correct dosage.

And in the pilot episode, it was J.D. and regular strength Tylenol.

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[–] shadowedcross@sh.itjust.works 18 points 18 hours ago (1 children)

It's people like this who make other people think any amount of painkillers is bad, and seem to get a sense of superiority about them for never taking any.

[–] ProgrammingSocks@pawb.social 6 points 17 hours ago* (last edited 17 hours ago) (1 children)

Even a little acetaminophen makes my liver feel funny the next day. Ibuprofen actually works for pain relief for me (migraines mostly) but it can cause stomach ulcers. Painkillers are definitely not something you can just use without thinking, and daily use especially can fuck your body up, ibuprofen is also hard on your kidneys.

Take the minimum effective dose as infrequently as possible.

[–] Ledericas@lemm.ee 6 points 15 hours ago

did you ever check your liver? that doesnt sound normal. with a small dose.

nsaids can cause bleeding and ulcers if itsa high dose. its because it inhibits cox 1 and 2, for clotting, and it works on your stomach by turning off inflammation, so your stomach can combat the acid with more mucus and cell turnover(inflammation increases cell turnover), thats why h pylori is a thing.

[–] sxan@midwest.social 27 points 20 hours ago (4 children)

You know what else is stupid? Pain management in the US. I get that you need to be careful about addiction, but the idea that people should have to suffer pain because we're having a pain medication "reefer madness" spasm is idiocy.

The guy just kept taking them until his teeth stopped hurting. Why is the alternative that he just has to put up with being in pain?

[–] RBWells@lemmy.world 7 points 15 hours ago

Yes it is. I have had, over my 40 years as migraineuse (they started in my teens) 5 intractable migraines. Meaning less than once every 5 years I get one that lasts days, I cannot eat or drink, just puke. I used to be able to go to my doctor and get shot up with opiates and Phenergan, so much of it, they would do one dose, come back later, another, another, another, until finally I would say "it still hurts but I don't care" and go home nodding like a junkie, sleep and wake up with no headache, and, importantly, NO desire for more drugs.

Now the opiates are not allowed because they didn't work. But nothing works on the status migraine. Now they give you a cold cocktail IV of some sort of Advil and nausea medicine and it doesn't work either, and costs $2,000 because it can only be done in the emergency room not the doctor office.

It's adding insult to injury. There has to be some way to make these available for acute situations at least.

[–] sulgoth@lemmy.world 27 points 20 hours ago (1 children)

The fact that the drug companies lied about the addictiveness of their product so doctors were handing them out like candy didn't help.

[–] Dozzi92@lemmy.world 11 points 18 hours ago

Yeah, it was rampant here in Jersey, and we're definitely still feeling the effects. Things that didn't need opiates got opiates. And guess what? Lotta people all of a sudden need them for life. And it wasn't just Oh, here's your script. Doctors were knowingly abusing it for profit. So like with most things in life, some people ruin it for everyone else.

[–] joel_feila@lemmy.world 6 points 15 hours ago

We have never had good pain management here. Claiming babies can't feel pain, black people hace higher pain tolerance, etc etc. then we swung into really permissive use with oxycodone for a while.

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[–] Damage@feddit.it 43 points 23 hours ago (6 children)

PSA: stupidity is dangerous

[–] Bytemeister@lemmy.world 32 points 23 hours ago (4 children)

Yeah, how long until this idiot cooks this liver too?

Honestly, getting a liver transplant in a week is the most unbelievable part of this story.

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[–] Ledivin@lemmy.world 78 points 1 day ago (13 children)

American here: I know paracetamol is acetaminophen, but how much is a packet?

[–] GreatAlbatross@feddit.uk 1 points 9 hours ago

Depends on the country I guess.

Here, a packet is 16 tablets of 500mg (acetaminophen) or 200mg (ibuprofen).

We're limited to 2 packets combined per purchase to reduce the chances of severe overdose.

Package dosing generally suggests 2 tablets per dose, with at least 4 hours between.
Or one tablet for children between 10 and 14.

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[–] then_three_more@lemmy.world 14 points 21 hours ago (6 children)

It's why in the UK shops won't sell more than 2 packets at a time. It's statistically reduced the amount of people killing themselves with them (intentionally or by mistake).

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[–] leadore@lemmy.world 10 points 19 hours ago* (last edited 19 hours ago) (1 children)

How much is a "packet"? edit: never mind, I found several conflicting answers in the other comments, no need to add even more and add to the confusion.

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[–] NocturnalMorning@lemmy.world 51 points 1 day ago* (last edited 21 hours ago) (9 children)

That guys a moron. The bottles are very very clear not to take more than the recommended dosage. Its labeled all over the bottle.

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