Granted. Your hyperactive immune system shuts down completely, thus preventing allergic reactions. You are now high-risk for every disease ever.
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Done in one.
Granted. Every species that causes you to have an allergic reaction has now ceased to exist.
I'm fine with this.
Get fucked dust mites.
Granted. You now have no eyes, nose or mouth to experience allergies via. Your face becomes a featureless expanse of skin.
Skin contact can trigger allergies. It's the mechanism behind poison ivy rashes, for example. Some people are "immune" because the chemical doesn't make their body attack itself.
This can actually trigger on subdermal tissues as well so if you follow this logic of removing exposure vectors it'd just strip all the flesh from your bones.
Huh. Yeah, of course. I feel like I knew that in some corner of my brain but it didn't click.
That solution is still very monkey's paw though.
Granted, you no longer has YOUR allergies... you've now got everyone's else allergies instead.