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I've been sad lately, watching the creaky old mice shuffling around my yard, so it's nice that there's something coming down the pipe to help them regain mobility.
That's awesome I ungrow cartilage and accelerate arthritis through jiu jitsu.
They need to redeem themselves because Stanford also gave us pedo parasite Peter Thiel
Stanford gave us much more than Peter Thiel
There is hope for my hands and wrists, maybe!
Arthritis causes bone damage too. So. Idk how it's going to regrow bone joints by repairing cartilage but I'm not a medical doctor.
I realize bone can repair itself but there are limits.
God damn no one here can let anything just be good
Doesn't bone damage start after cartilage is gone?
Sort of but yeah. As the cartilage breaks down the bone joints start making direct contact. Wearing the ball ends and socket. The ball ends get worn down to where there isn't much of a ball shape and the socket gets the sides worn out so that it's basically a very shallow wide bowl. So the joint can dislocate easier but mostly the problem people have is the bone on bone rubbing.
I guess I was thinking about hip replacements. That kind of damage isn't going to be fixed with better cartilage. Its too late. But better cartilage would surely improve outcomes of such a surgery.
And possibly slow down degeneration if caught early.
Interesting. That makes sense when I imagine the physics of it.
Perfect is the enemy of good.
man all the shit that works on mice
we must have made super jacked non-aging bio mice by now
seriously though hope this transfers, shitty joints just suck, no fun at all - signed an algae oil drinker
Hey I know of a pool where you can get a whole bunch of algae right now...
is that the american one? glad to see even minor issues like a pool can get our attention but they couldn’t even point to nz on a map
Skaven funding lol
Some of us already do bro.. just the other day I told off a fella “never speak to me or my super jacked non-aging bio mouse again”
At this point we could probably breed mice that we can remote control and use to spy on people or use as a bio IED drone.
This drug has already gone through Phase 1 human trials for a separate condition.
Phase 1 trials only test safety in healthy adults, but this drug passed. (Still awaiting the paper on the trial)
The delivery method was a once a day pill.
Right? After a lifetime of walking, I'm gonna need some work soon -- feet, mainly. Please let this get to an applicable fix before it's too late!
I think a part of getting older is just watching medical science get better as the world gets shittier and realising the two cancel each other out so a natural death is still the preferred option. This is probably how people felt off the back of a world war, the depression, and then in the middle of another world war, someone's like,
"Check out penicillin! I accidentally discovered it like a decade ago."
"Nah, I'm good, thanks."
Yeah my dad was discussing MAID (medically assisted death) recently, he is in his late 70s.
He lost his heel in a motorcycle accident in the 1970s and they butchered up his right inner thing taking a chunk out and putting it on his foot. So now both his legs are in constant pain and he spends most of his day high as a kite to deal with the pain. He can barely walk anymore. He got through cancer a few years back which made matters worse and he lost his sense of taste so he gets to be in pain all day and not taste anything enjoyable.
Nothing medical is going to improve his life drastically so if MAID is what he wants then I will support him.
Oh shit this is awesome. I’ve got some stuff that’s wrong with my knees, and this would be fantastic.
My wife recently had her knee replaced. After seeing her recovery, hopefully this is available before I need mine done. Otherwise, it's gonna have to hurt like hell non stop before I consider getting mine done.
Semaglutides and other weight loss drugs will hopefully make this treatment less needed in the future. I hope this somehow gets funding, testing, and approval before then to help all the folks with existing damage.
Too bad insurance in the US doesn't cover them for weight loss.
It will in 2032 when the cheap stuff is allowed here.