this post was submitted on 06 Apr 2025
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[–] entwine413@lemm.ee 17 points 1 year ago* (last edited 1 year ago) (4 children)

There are 100% people with a gene that makes them metabolize anesthesia super rapidly, myself included. It's linked to the gene for red hair, but red hair isn't a requirement (I have it and I'm not a redhead, although my mom is).

I've 100% woken up during surgeries I should not have been conscious for, because the anesthesiologist didn't believe me. Those include a pediatric colonoscopy, surgery to set a broken arm, my TEE (I was conscious, but in twilight sleep. Took 3 vials of versed and I still remember it), and my septoplasty.

And it's not just general anesthesia either. It takes a fuck load of local anesthesia for me to feel it. My last filling they had to give me so much it paralyzed half my face for a while. Also, I wish my urologist had believed me when I said I wasn't numb for my vasectomy.

[–] tischbier@feddit.org 7 points 1 year ago

What’s up cousin! I have this gene. Also have EDS and we have a ton of red hair in our family.

I also woke up during a pediatric surgery! Mine was a facial surgery. I was out for a bit and near the close end I woke up and was aware of everything except the pain.

Thanks for letting me know about the vasectomy pain because those are supposed to be easy! Yikes sorry man.

I wish we could add this to our medical files. Like it should be easy to do but for some reason it always comes down to the patient and whether the doctor feels like believing them that day.

Bonus: We also process opioids rapidly. So, those don’t work on us either. But the trade off is we have higher pain thresholds than normal people.

[–] SirQuack@feddit.nl 4 points 1 year ago (1 children)

Also, I wish my urologist had believed me when I said I wasn't numb for my vasectomy.

I was undersedated for that one too. Hurt like a mother, but I never realised I may be under sedated so I just challenged through.

No issues in the end though. Just a firm reminder to ask for a double dose next time.

[–] entwine413@lemm.ee 4 points 1 year ago

I straight up told mine I require significantly more anesthesia because of my genetics. He made the incision, asked if I felt it, I said yes, then he started.

I did find out that I have an enormous pain tolerance, though. Fortunately the recovery was a breeze, so I guess I speed ran the pain.

[–] stetech@lemmy.world 3 points 1 year ago (2 children)

How interesting! Does this apply to alcohol/other “recreational” drugs too, then, or only sedative ones?

[–] entwine413@lemm.ee 3 points 1 year ago

I'm pretty resistant to stimulants, but I have ADHD so that skews this.