Danger Dust

In conclusion, this study demonstrates the anthelmintic properties of stonefish ichthyocrinotoxins and highlights their potential as novel therapeutics. While both S. horrida and S. verrucosa ichthyocrinotoxins showed activity against skin-burrowing hookworm larvae, the isolated small component mixture from S. horrida ichthyocrinotoxin emerged as the most promising drug lead due to its increased potency to the parasite, favourable size for drug development, and reduced cytotoxicity compared to the crude extract. However, further isolation and identification of the active component(s) within S. horrida ichthyocrinotoxin are needed to fully determine its clinical relevance.