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Just three molecules can launch gene-silencing condensates in stem cells (phys.org)

submitted 9 hours ago by rss@news.abolish.capital to c/ecosocial@news.abolish.capital

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A new study has uncovered how an exceptionally scarce protein can orchestrate the assembly of large-scale gene-silencing structures inside cells, and what happens when that process breaks down. The findings, published today in Molecular Cell, identify a self-clustering mechanism in the Polycomb protein CBX2 that is essential for initiating the formation of gene-repressive condensates and guiding stem cells toward their proper fates.

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