There are programs that will play midi files with arbitrary instruments, if you don't find an all-in-one solution.
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Sounds like you might want a DAW (Digital Audio Workstation).
These are a little "heavy duty" for what you want and you will need one that support sheet music style notation but I think you should check out Reaper.
This video is pretty old but should be applicable still:
For instruments checkout the BBC symphony orchestra plugin here:
https://www.spitfireaudio.com/en-us/collections/bbc-symphony-orchestra
Funny enough I use that BBC Orchestra VST for almost all my strings, including this track:
Concentrated Destruction by Thassodar on #SoundCloud https://on.soundcloud.com/frnrP5VTdloQvWsqUk
I'd also recommend Ableton, my DAW of choice, as it comes with several built-in MIDI instruments and powerful stock audio effect plug-ins.
Musescore might be able to do what you need? I believe it has on-screen keyboard as an option for note input, and the last reply in this thread has info for importing PDFs of sheet music.