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So if he gave his family polio it would be equivalent to shooting himself and wife, and hitting his kids in the face with a shovel. Manslaughter you say
Given polio's deadliness it would be much easier to get a murder conviction in that situation, sure. You'd still have to prove it was intentional though, because that is still the definition of murder. If a defence case is that the accused is not guilty of murder because they didn't intend to kill the victim, and the jury isn't sure that's not true, they mustn't convict.
You mentioned "negligence" in your comment above. If you're claiming negligence, that is going to, by definition, fall under manslaughter laws. In some jurisdictions there is even the charge of "gross negligence manslaughter" which this would probably fall under.
Even the treatments in the past are surreal if you haven't seen them. The "Iron Lung"
I saw people older than me in the 70s with limps, dead arms, braces and the reason was always polio.
But then God intervened and stopped it that same summer as the Salk vaccine was used.