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Anti-Aging Injection Regrows Knee Cartilage and Prevents Arthritis (scitechdaily.com)

submitted 5 days ago by Lemmar@lemmy.today to c/science@lemmy.world

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In mice (of course) and human tissue exvivo. Earlier phase 1 studies with 15-PGDH has shown that it is safe and active in healthy volunteers.

Reference: “Inhibition of 15-hydroxy prostaglandin dehydrogenase promotes cartilage regeneration” by Mamta Singla, Yu Xin Wang, Elena Monti, Yudhishtar Bedi, Pranay Agarwal, Shiqi Su, Sara Ancel, Maiko Hermsmeier, Nitya Devisetti, Akshay Pandey, Mohsen Afshar Bakooshli, Adelaida R. Palla, Stuart Goodman, Helen M Blau and Nidhi Bhutani, 27 November 2025, Science. DOI: 10.1126/science.adx6649

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[–] SkunkWorkz@lemmy.world 21 points 5 days ago (2 children)

Bet soon I can buy this from a roided up guy in the locker rooms of my local gym. Middle aged power lifters would love to pop these pills.

[–] musubibreakfast@lemmy.world 3 points 4 days ago

"I just popped a kneecap, it shot clean off and broke a mirror. Pill me babay!"

[–] Lemmar@lemmy.today 1 points 4 days ago (1 children)

Most definitely. I'm almost in that demographic myself and several of the slightly older, nerdy lifters at my gym talk about BPC-157 as something they would consider using.

If this gets proven to work in vivo in humans I'm certain we'll see the same no matter side effects.

[–] blarghly@lemmy.world 1 points 2 days ago

I've also heard the peptide hype. I'm curious, as an aging athletic person - but also I don't want to roll the dice with cancer