Here is a side by side of his two last videos, one month apart.
In the comments he said he was sick with the flu, it looks more serious then that.
The dramatic weight loss, the loss of fat around the face, the skin color, and the hand bandage.
I've really enjoyed his content, fallen asleep to his videos. I hope he is ok and will recover quickly, but the dramatic change has me speculating something more serious then the flu.
he has some videos detailing his progress in his free tier patreon.