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Antidepressants linked to faster cognitive decline in dementia, study suggests (www.sciencedaily.com)

submitted 1 month ago by [email protected] to c/[email protected]

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cross-posted from: https://lemmy.world/post/26326122

New research suggests that certain antidepressants can accelerate cognitive decline in people with dementia. At the same time, some drugs appear to be less harmful than others, which can help doctors make better treatment decisions, according to the study.

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[–] [email protected] 19 points 1 month ago

Key paragraph, for anyone wondering which specific drugs are implicated:

The study also points to differences between different drugs. The SSRI [selective serotonin reuptake inhibitor] escitalopram was associated with the fastest cognitive decline, followed by the SSRIs citalopram and sertraline. Mirtazapine, which has a different mechanism of action, had less negative cognitive impact than escitalopram.