At the end of the day, enough empirical data over a long enough time frame will have to do, especially if there are no alternatives. Sure do like me a good mechanism though, especially for new things, gives a clue as to long term side effects.

[–] ChunkMcHorkle@lemmy.world 2 points 1 week ago

I heard that in Fillion's voice, lol. Shiny.

[–] Natanael@slrpnk.net 3 points 1 week ago

Genuinely, we're better at preventing memory formation and experience of pain than actual sedation. Patients can be cognitively present, and the reason they're not traumatized from a experiencing a surgery is that we're preventing the experience from leaving a mark on the brain

https://pubmed.ncbi.nlm.nih.gov/40626585/