Another thread worth pulling is that biotechnology and synthetic biology have turned out to be substantially harder to master than anticipated, and it didn't seem like it was ever the primary area of expertise for a lot of these people anyway. I don't have a copy of any of Kurzweil's books at hand to look at his predicted timelines for that stuff, but they're surely way off.
Faulty assumptions about the biological equivalence of digital neural network algorithms have done a lot of unexamined heavy lifting in driving the current AI bubble, and keeping the harder stuff on the fringes of the conversation. That said, I don't doubt that a few refugees from the bubble-burst will attempt to inflate the next bubble on the back of speculative biotech, and I've seen a couple of signs of that already.
Obvious joke is obvious, but
Harvard isn't already full of Quarks?