Description: A five panel comic. In the first picture the main character leaves and a co-worker says "See ya, dude". In the second panel, the protagonist is in a supermarket and the cashier says "Hey man." In the third panel, the protagonist is on a train and someone on the phone says "Hello, sir." In the fourth panel, the protagonist enters an apartment and says "I' home." and is welcomed by a woman who rushes towards her and says "THERE she is!" The two of them hug in the fifth panel, while the woman says "How's my beautiful girlfriend doing??"
Art by Homunculus101
Varies from person to person. In general I wouldn't worry about it too much, the way those are used is pretty gender neutral in general even though they can contextually be male. If you know you're addressing a trans gal maybe make more of an effort for folks but I wouldn't worry about it too much. If someone tells you it bothers them, then ya know, try not to. In general the litmus test for me is would it be a problem if they were cis? If not, then not a problem by default (if it bothers them, it's an exception to account for)
Overall, I think it's silly to be concerned over the use of guys and dudes instead of the tendency to treat everyone on the Internet as male.
The fact you want to be considerate puts you far ahead of the crowd!
I'd agree but not having to deal with theoretically gender neutral terms is a bit annoying. In German it is especially annoying because of the frequent use of generic masculine which is annoyingly common outside queer and feminist spaces.