Science

New research from CSHL Associate Professor Tobias Janowitz, WashU Medicine Professor Adam Kepecs, and their collaborators reveals a circuit in the brainstem that can sense inflammation and drive apathy-like behavior in cancer cachexia. Janowitz is a co-team lead for CANCAN, tackling the cachexia challenge set in 2020 by Cancer Grand Challenges, a research initiative co-founded by Cancer Research UK and the National Cancer Institute.

Researchers from Penn have found new cost-effective ways to make a great cup of pour-over coffee using fewer beans. Their findings could potentially provide insights into similar systems such as waterfalls and surface erosion.

Childhood maltreatment often continues from one generation to the next, perpetuating the cycle of abuse and depression. In a bid to promote healthier parent-child relationships, researchers from the University of Fukui compared mothers who engaged in maltreatment with those who did not, revealing that childhood trauma increases emotional empathy and depressive symptoms, raising the risk of abusive parenting. Their findings highlight the need for mental health support and parenting programs to help break this cycle.

Let’s start with what should be obvious: The wolf pups are not dire wolves, and they haven’t been “de-extincted.”

The fluffy white canines — Romulus, Remus, and Khaleesi — unveiled this week by Colossal Biosciences are closer to something like designer dogs. More precisely, they are genetically modified, hybridized modern wolves, gestated in the womb of a domestic dog. But that wouldn’t sound as impressive on a magazine cover.

Far beneath the Pacific Ocean, off the coast of Vancouver Island, a seemingly dormant underwater volcano has revealed a breathtaking secret—one that has left scientists both thrilled and puzzled. What began as a geological survey quickly turned into a remarkable biological discovery: a hidden nursery where thousands—possibly over a million—giant eggs are incubating in the warm embrace of volcanic heat.

Back in 2019, researchers from Fisheries and Oceans Canada launched a deep-sea mission to explore a 2,000-square-kilometer seamount that rises more than 1,100 meters above the seafloor. Initially believed to be extinct, the volcano surprised the team by venting mineral-rich hot water, a clear sign of ongoing geological activity. This natural heat source has created a rare haven for marine life, especially deep-sea corals and sponges.

But the true marvel came when the scientists spotted white skate rays (Bathyraja spinosissima) laying eggs in droves across the summit of the volcano—1.5 kilometers below the surface.

While deep-sea rays aren’t new to marine biologists, what stunned the team was the sheer scale of this reproductive gathering. Based on initial counts and image surveys, experts believe the site could be home to hundreds of thousands, possibly over a million eggs—a number that has never before been documented for this species.

What’s even more astounding is the size of the eggs themselves. These rays produce egg cases nearly 50 centimeters in length, resembling soft, curved pillows or even ravioli in shape. That’s massive by marine standards. Producing such energy-intensive eggs is a strategy that ensures each embryo has ample nutrients to survive the harsh conditions of the deep sea.

White skate rays typically dwell between 800 and 2,900 meters deep, making them difficult to study. But scientists now believe these females may be strategically using hydrothermal warmth to speed up embryonic development—a biological shortcut in a cold and slow world. According to marine biologist Cherisse Du Preez, incubation in this harsh environment can take up to four years, but the residual heat from the volcano may significantly reduce that time.

And it’s not just about warmth. The volcano’s summit offers shallower, more protected terrain, where vulnerable hatchlings can grow before venturing into deeper, more dangerous waters.

This rare convergence of geology and biology offers researchers a one-of-a-kind opportunity to study how extreme environments influence life. Just like the vents discovered near the Galápagos years ago, this site proves that even the harshest locations can nurture complex life.

The adaptive strategy of these rays—laying large eggs in volcanically active zones—shows an evolutionary brilliance that has likely gone undetected for centuries. And while we may never know exactly what other species share this hidden volcano habitat, it’s a strong reminder of how much there still is to explore below the surface.

As the mystery of the million eggs unfolds, it brings with it a renewed urgency to protect deep-sea ecosystems. These volcanic oases are fragile, and with deep-sea mining and climate change threatening marine habitats globally, discoveries like this underscore the need for responsible exploration and global cooperation in preserving what we’ve only just begun to understand.

This isn’t just a story about a volcano or even about a rare marine species. It’s a reminder that the deep ocean holds secrets more profound than we can imagine—secrets that challenge our understanding of life and force us to look again at how interconnected our planet truly is.

I know that m1u1 + m2u2 = m1v1 + m2v2 Can any one prove that to me.

In the Amazon, gold mining is a thriving business, pushing deep into the rainforest and indigenous lands. Small-scale operations set up primarily illicitly and operated in the shadows use mercury, a substance with neurotoxic properties, for gold extraction. Now, a team of researchers examined if trees native to the Peruvian Amazon could be used as biomonitors for gold mining activities. By examining mercury concentrations in tree rings, they concluded that some species could bear witness to illegal mining activities.