this post was submitted on 29 Dec 2025
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The president had yet another strange mark on his hands over Christmas, once again raising concerns that his health is not what he has claimed it to be.

Donald Trump—the oldest person to ever be elected president—was photographed with what appeared to be another bruise on Christmas Eve, this time marring his left hand.

The 79-year-old has repeatedly claimed that he is in pristine condition, brushing off public alarm over his deteriorating body.

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[–] daannii@lemmy.world 42 points 5 days ago* (last edited 5 days ago) (17 children)

Some people speculate is dementia drug infusions.

I did work for about a year doing pharm research for Alzheimer's. Most of those drugs are infusions.

However. None of them stop or reverse loss.

They just slow it down And they aren't even that effective. Honestly the data I saw.... My opinion was. :

-Desperate people are going to pay this $1200 a month infusion cost for literally no benefit and extra risks.

Based on the documents I read, for one of the drugs we were testing (I forget the drug but I recall it's already used to treat ALS)-

The dosage needed to cause a change in Alzheimer's would have a serious health risk of brain bleeding.

The dose we were using was like 1/3 of the expected effectiveness dosage.

I thought this was kind of unethical because people signed up to be in the study with the hope of a medicine that would help them. And that's how it was presented to them.

However. The study was really just trying to see how much brain bleeding occured at 1/3 dose.

With zero expectations for actual effectiveness on slowing down the progress.

I did not like the ethical issues with this line of work.

Anywho I have gotten on a tangent.

The other thing I wanted to say is , if these drugs are to have any effects in slowing (but none stop or reverse , just to be 100% clear on this), then the person MUST start them with early symptoms. What is called "mild cognitive impairment".

They do nothing if symptoms are already noticeable.

And most people don't realize they have dementia until it's already moderate because they mask their symptoms. Or their symptoms are often excused because "pops/Mom is getting old and that's normal".

Its progressive.

Slow at first. And most don't notice until it's gotten pretty bad.

Trump almost certainly has fronto temporal dementia.

I'm not the only neuroscientist to say so.

I'm not clinical but I did work with dementia patients. Plus many clinicians are saying the same.

He's got classic text ook symptoms.

People excuse his word salad because it slowly got worse.

But read out loud anything he writes or says.

It's nonsense. That's not normal. Read this and it's a good example of Trump's speech patterns.

https://en.wikipedia.org/w/index.php?title=Logorrhea_%28psychology%29&wprov=rarw1

-In a more extreme version of logorrhea aphasia, a clinician asked a male patient, also with Wernicke's aphasia, what brought him to the hospital. The patient responded:

-Is this some of the work that we work as we did before? ... All right ... From when wine [why] I'm here. What's wrong with me because I ... was myself until the taenz took something about the time between me and my regular time in that time and they took the time in that time here and that's when the time took around here and saw me around in it's started with me no time and I bekan [began] work of nothing else that's the way the doctor find me that way ...[5]

[–] firebyte@lemmy.world 2 points 4 days ago* (last edited 4 days ago) (2 children)

The dosage needed to cause a change in Alzheimer's would have a serious health risk of brain bleeding.

Do all of these drugs have this risk? It starts to line up when it was alleged Trump's team freaked out about Trump apparently having a 'mini-stroke' whilst meeting Putin (someone else in this thread), and when Trump was photographed earlier this year with a visible facial droop on his right side...

https://www.yahoo.com/news/articles/trump-facial-droop-9-11-002129721.html

[–] daannii@lemmy.world 2 points 4 days ago (1 children)

Any drug that targets the plaque and tau proteins has that risk because the drug action is to break up stuff in the brain. Which can damage small blood vessels.

[–] firebyte@lemmy.world 2 points 4 days ago

Good to know, thanks!

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