Long story short Activity Pub only pulls the content it needs from remote servers when it needs it and can choose how to handle media (serve the original or cache and proxy). It already is similar-ish to a CDN.
AT-Proto is super complex, but my understanding is that a new server (app in AT-Proto parlance) needs to copy everything beforehand from all others, and needs to constantly replicate everything, wether it will be served or not, making the data transfers intractably massive.
Not only is Ghostery redundant when you use uBlock Origin (you can choose the tracking removal lists, like EasyPrivacy, for example), Ghostery has a conflict of interests as it works with the ads industry at the same time it has this tool, and it reports the ads and tracking it finds back to advertisers, who can then make them bypass that detection better.
If you insist in a separate add-on, Privacy Badger does the same blocking of trackers and it is maintained by the Electronic Frontier Foundation, a non-profit for digital privacy.